Dermatoglyphics in Darier's Disease

Abstract

9 cases of Darier's disease were studied. All probands showed typical clinical lesions of Darier's disease. The clinical diagnosis was confirmed by histopathological study. Study of palmar dermatoglyphics by the standard Ink and Roller method revealed certain characteristic features. Whorl pattern was the predominant finger tip pattern observed in both sexes. Ridge Dissociation, wide flexion don creases, white lines and white dots were the main features found in those cases. Sydney line and extra digital transverse crease were also observed. The finger tip pattern in famale probands was found to be statistically significant when compard with that of controls.As significant dermatoglyphic findings have been oberved in the present study, an analysis of the palmar dermatoglyphics can be used as an important tool of significance in the study of Darier's disease . As the development of dermatoglyphic pattern in utero is strongly influenced by genetic factors, it is worthwhile, applying this mathematical science of genetics in various genodermatoses.