A Randomized Double Blind Study of Ointment Containing Diflucortolone Valerate and Hydrocortisone Acetate

Abstract

DiflucortolonevalerateO.1percentand hydrocortisone acetate 1.0 percent were compared in a randomized double blind contralateral, intra individual trial in fifty-two patients. Duration of treatment was three weeks. Both the drugs showed significant response after the first second and the third weeks of treatment. At all periods the reduction in pre-treatment signs and symptoms was greater for diflucortolone as compared to hydrocortisone. Response to therapy in eczema was very good in 89.1 percent cases and good 10.9 per cent. Patients having psoriasis and chronic DIE showed very good response in 33.3 per cent and good in 66.6 per cent cases. There were no side effects.