Multiple Keratocanthomas on the Mons Pubis and Labia Majora

Abstract

An ederly woman developed multiple keratoacanthomas on the mons pubic and labia majora. Some lesion coalesced to from large irregular plaques with multiple craters. Biopsy of a well developed nodule revealed keratin - filled craters, pseudoepitheliomatous hyperplasia with horn pearls and dyskeratosis of prickle cells which appeared eosinophilio and glassy. Though a few lesions involuted spontaneously, some persisted. These responded well to topical 5-fluorouracil therapy. There was no recurrence of lesions, on long follow-up