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A comparative study of efficacy of cetirizine versus astemizole in chronic idiopathic urticaria
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Vijay M, Rawal R C, Billimoria F E. A comparative study of efficacy of cetirizine versus astemizole in chronic idiopathic urticaria. Indian J Dermatol Venereol Leprol 1994;60:272-274
AbstractEfficacy of Cetirizine and Astemizole was compared in 50 cases of chronic Idiopathic urticaria. Patients were divided into 2 groups viz A and B. Before starting the therapy, routine investigations were carried out to rule out any septic focus. Prior to treatment, 1 week before all medications were withdrawn. Cetirizine and Astemizole, 10mg each, were given as a single daily morning dose for 1 month and patients were followed up for 1 month.
40% excellent response was observed with Cetirizine while 20% excellent response with Astemizole. Good response was observed in 32% patients with Cetirizine and 28% with Astemizole. No side effects were observed except sedation, 8% in Cetirizine group and 20% with Astemizole group.