Direct immunofluorescence in lesional and uninvolved skin in dle
C R Srinivas
P S G Medical college, Peelamedu, Coimbature, Tamil Nadu 641 004
|How to cite this article:
Sandra A, Srinivas C R, Balachandran C, Shenoi S D. Direct immunofluorescence in lesional and uninvolved skin in dle. Indian J Dermatol Venereol Leprol 1998;64:150-152
AbstractDirect immunofluorescence was evaluated in 16 patients with DLE including 1 case of lupus profundus and 4 with disseminated DLE. A BMZ band with multiple immunoreactants was demonstrated in lesional skin in 14 patients (87. 5%), while 2 had only single immunoreactants. C3 and IgM were the commonest reactants followed by IgG, Ig A and fibrinogen. A perifollicular prominence was seen in several patients. Four patients showed a band in uninvolved skin. This may indicate a potential to develop SLE. ANA was also positive in 5 patients but ds DNS was negative.