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Arsenical keratoses with squamous cell carcinoma
Corresponding author: Dr. Shekhar Neema, Department of Dermatology, AFMC, Pune - 411 040, Maharashtra, India.shekharadvait@gmail.com
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Received: ,
Accepted: ,
How to cite this article: Neema S, Radhakrishnan S. Arsenical keratoses with squamous cell carcinoma. Indian J Dermatol Venereol Leprol 2022;88:376-7.
A 60-year-old man, residing in Murshidabad, West Bengal, presented with multiple, painless, asymptomatic raised lesions over palms and soles of 4-years duration. On cutaneous examination, both palms showed multiple, hyperkeratotic papules. A solitary 2 × 2 cm ulcero-proliferative growth with sero-sanguineous discharge was seen over the thenar eminence of the right hand [Figure 1]. Histopathological examination of the ulcero-proliferative lesion was suggestive of moderately differentiated squamous cell carcinoma. Arsenic content as measured in hairs and nails was high (normal values: up to 0.61 mcg/gm for hairs and up to 0.23 mcg/gm for nails). He was diagnosed as a case of arsenical keratoses with squamous cell carcinoma and treated with surgery and chemotherapy.
- Multiple hyperkeratotic papules (arsenical keratoses) involving palmar aspect of the right hand. A 2 cm × 2 cm, ulceroproliferative growth over the thenar eminence of the right hand
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Conflicts of interest
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