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Letter in Response to Previous Publication
87 (
1
); 63-63
doi:
10.25259/IJDVL_1041_20

Authors’ reply

Departments of Dermatology and Venereology All India Institute of Medical Sciences, New Delhi, India
Departments of Pathology, All India Institute of Medical Sciences, New Delhi, India
Corresponding author: Dr. Sujay Khandpur, Department of Dermatology and Venereology, All India Institute of Medical Sciences, 4th Floor, Teaching Block, New Delhi - 110 029, India. sujay_khandpur@yahoo.com
Read LETTER associated with this article - 10.25259/IJDVL_869_20
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This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Sondhi P, Singh S, Khandpur S, Agarwal S. Authors’ reply. Indian J Dermatol Venereol Leprol 2021;87:63.

Sir,

Thank you for allowing us to reply to the letter to the editor titled “There is more to the ‘intracellular yeasts’ than meets the eye.” We thank the authors for adding to the differential diagnosis of intracellular yeasts ranging from 2–4 m. We agree that molecular sequencing may help to accurately diagnose morphologically similar fungi.

However, these advanced methods require sophisticated technology, manpower and money. These advanced tests are not available to all. We diagnosed our patient as histoplasmosis with unusual cutaneous manifestation, based on clinical and histomorphological features. Our patient had a history of proximity to pigeons for a long time. He had prior involvement of adrenal and laryngeal tissues which have been commonly described in histoplasmosis. The patient also responded predictably to itraconazole.

Emergomyces appears to be a new emerging fungus.1 In comparison to histoplasmosis, it appears to be associated with more immunocompromised status, has more widespread lesions and though morphologically characterized by intracellular yeasts measuring from 2–4 m, it does not have a peri-yeast halo as described in histoplasmosis.2

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

  1. , , , , , , et al. Emergomyces: The global rise of new dimorphic fungal pathogens. PLoS Pathog. 2019;15:e1007977.
    [CrossRef] [PubMed] [Google Scholar]
  2. , , , , , , et al. Disseminated emergomyces pasteurianus infection in India: A case report and a review. Mycopathologia. 2020;185:193-200.
    [CrossRef] [PubMed] [Google Scholar]

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