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Chemoprophylaxis in Pyodermas
Gurmohan Singh
,
Correspondence Address:
Gurmohan Singh
Correspondence Address:
Gurmohan Singh
How to cite this article: Singh G. Chemoprophylaxis in Pyodermas. Indian J Dermatol Venereol Leprol 1974;40:181-184 |
Copyright: (C)1974 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Effect of prophylactic use of-antibiotics for preventing staphylococcal infections of skin was studied experimentally. Healthy human volunteers were given pencillin or demethylchlor tetracycline in usual therapeutic doses -and later challenged with staphylococci. In 2 of 3 subjects, the prophylactically given drug could not ;prevent the experimental infection, even though the challenging organisms were sensitive to the respective antibiotics in vitro. When the drug was continued even after the staphylococci were inoculated, 50% showed evidence of clinical infection. Diphtheroids had complete disappearance and staphylococcus epidermidis became resistant to the antibiotic used even though its quantum remained at a constant level.Fulltext Views
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