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Clothing-facilitated allergic contact dermatitis to chloroxylenol: Symmetrical thigh erythema in an occupational cleaner
Corresponding author: Dr. Ping Wang, Department of Dermatology, Hangzhou Third People’s Hospital, Affiliated to Zhejiang Chinese Medical University, Hangzhou, China. dermwang@aliyun.com
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How to cite this article: Jin S, Jin S, Wang P. Clothing-facilitated allergic contact dermatitis to chloroxylenol: Symmetrical thigh erythema in an occupational cleaner. Indian J Dermatol Venereol Leprol. doi: 10.25259/IJDVL_675_2025
A 60-year-old male cleaner presented with a 5-month history of symmetrical, well-demarcated, erythematous plaques on the inner thighs [Figure 1], accompanied by pruritus. Occupational exposure involved frequent kneeling and use of a chloroxylenol-containing cleanser (0.1%), which soaked through work pants. Patch testing with the cleanser “as is” elicited a 2+ reaction (ICDRG-International Contact Dermatitis Research Group criteria), while controls were negative. The cleanser’s pH (6.8) and absence of irritants excluded irritant contact dermatitis. Complete lesion resolution followed discontinuation of allergen exposure and treatment with topical fluticasone propionate 0.05% ointment (applied twice daily to affected areas for 2 weeks) combined with oral cetirizine 10 mg once daily. Symptoms resolved after discontinuation. This case highlights clothing-facilitated allergic contact dermatitis in non-occluded areas, emphasising mechanical friction and allergen retention in atypical occupational dermatitis.
- Well-defined, semi-circular, symmetrical erythematous plaques with mild dryness and scaling on both inner thighs.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent.
Financial support and sponsorship
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Conflicts of interest
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.
