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Studies
PMID: 20953017
Comparison of topical methenamine, glutaraldehyde and tap water iontophoresis for palmoplantar hyperhidrosis
VA Phadke, RS Joshi, US Khopkar, SL Wadhwa
Department of Skin and STD, BYL Nair Charitable Hospital, Bombay - 400008, India
Correspondence Address:
V A Phadke
3-Anandvan, Sahitya Sahawas, Gandhi Nagar, Bandra (E), Mumbai - 400051
India
Correspondence Address:
V A Phadke
3-Anandvan, Sahitya Sahawas, Gandhi Nagar, Bandra (E), Mumbai - 400051
India
How to cite this article: Phadke V A, Joshi R S, Khopkar U S, Wadhwa S L. Comparison of topical methenamine, glutaraldehyde and tap water iontophoresis for palmoplantar hyperhidrosis. Indian J Dermatol Venereol Leprol 1995;61:346-348 |
Copyright: (C)1995 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Sixty patients with palmo-plantar Hyperhidrosis were studied to compare the efficacy and safety of topical methenamine in the treatment of palmo-plantar hyperhidrosis with established therapies like glutaraldehyde and tap water iontophoresis. Patients were randomly allocated to 3 treatment groups: topical Methenamine (10%) solution, topical Glutaraldehyde (5% for palms and 10% for soles) and tap water iontophoresis.Hyperhidrosis was graded into 4 grades. The total duration of therapy was 4 weeks for all the 3 groups. Patients were followed up weekly for 4 weeks and 2weeks after completion of therapy. Response to therapy was evaluated by the change in the grade of hyperhidrosis. Side-effects like irritation and pigmentation were looked for at every follow up. Wilcoxon’s rank sum test was used for comparison between changes in grading of 2 groups. It showed that methenamine is superior to tap water iontophoresis and acts faster than glutaraldehyde. Fewer side effects were noted with mether amine.
Keywords: Palmoplantar hyperhidrosis, Methenamine, Glutaraldehyde, Iontophoresis
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