Translate this page into:
Cutaneous granular cell tumour (Abrikossoff’s tumour) of the abdomen with a setting sun dermoscopic pattern
Corresponding author: Dr. Maha Lahouel, Department of Dermatology, Farhat Hached University Hospital of Sousse, Sousse, Tunisia. mahalahouel@gmail.com
-
Received: ,
Accepted: ,
How to cite this article: Lahouel M, Amor F, Denguezli M. Cutaneous granular cell tumour (Abrikossoff’s tumour) of the abdomen with a setting sun dermoscopic pattern. Indian J Dermatol Venereol Leprol. doi: 10.25259/IJDVL_1291_2025
A 53-year-old woman presented with a solitary, asymptomatic, yellowish abdominal nodule that had slowly enlarged over three years. Examination revealed a yellowish-red, well-defined, firm, and mobile tumour measuring 1 x 1.5 cm, located on the right side of the upper abdomen [Figure 1a]. Dermoscopy showed a yellow-orange center with an erythematous border and lighter peripheral pigmentation, resembling a “setting sun” pattern [Figure 1b]. A wide excisional biopsy was performed. Histology showed diffuse dermal infiltration with tumoural nests. These cells had central nuclei and eosinophilic cytoplasmic granules. Immunohistochemistry showed strong positivity for S100, neuron-specific enolase, and CD68, confirming granular cell tumour (Abrikossoff’s tumour) [Figure 2a-d]. No recurrence was noted after six months.
- Yellowish-red, well-defined abdominal nodule (3 cm).
- Dermoscopy showing a yellow-orange center (black star), erythematous border (red arrow), and lighter peripheral pigmentation (black arrow), forming a ‘setting sun dermoscopic pattern’, polarised, 10x.
- Diffuse dermal infiltration with tumoural nests (Haematoxylin & eosin, 40x).
- Neoplastic cells with central nuclei and eosinophilic granules (black arrows) (Haematoxylin and eosin, 200x).
- Positive immunostaining for S100, (200x).
- Positive immunostaining for CD68, (100x).
Declaration of patient consent
Patient’s consent not required as there are no patients in this study.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.