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Clinical Studies
PMID: 20921748
Direct immunofluorescence in lesional and uninvolved skin in dle
A Sandra, CR Srinivas, C Balachandran, SD Shenoi
department of Dermatology, Kasturba Medical College, Manipal- 576119, karnataka, India
Correspondence Address:
C R Srinivas
P S G Medical college, Peelamedu, Coimbature, Tamil Nadu 641 004
India
Correspondence Address:
C R Srinivas
P S G Medical college, Peelamedu, Coimbature, Tamil Nadu 641 004
India
| How to cite this article: Sandra A, Srinivas C R, Balachandran C, Shenoi S D. Direct immunofluorescence in lesional and uninvolved skin in dle. Indian J Dermatol Venereol Leprol 1998;64:150-152 |
Copyright: (C)1998 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Direct immunofluorescence was evaluated in 16 patients with DLE including 1 case of lupus profundus and 4 with disseminated DLE. A BMZ band with multiple immunoreactants was demonstrated in lesional skin in 14 patients (87. 5%), while 2 had only single immunoreactants. C3 and IgM were the commonest reactants followed by IgG, Ig A and fibrinogen. A perifollicular prominence was seen in several patients. Four patients showed a band in uninvolved skin. This may indicate a potential to develop SLE. ANA was also positive in 5 patients but ds DNS was negative.
Keywords: Direct immunofluorescence, Discoid lupus erythematosus, lupus band
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