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Drug-Induced pseudolymphoma syndrome
R R Mittal
Department of Dermatology and Venereology, Government Medical College, Patiala-147 001
|How to cite this article:
Mittal R R, Jain C, S Walia R L, Chopra A. Drug-Induced pseudolymphoma syndrome. Indian J Dermatol Venereol Leprol 1995;61:94-95
Five cases of pseudolymphoma syndrome (PS) in children aged six to twelve years were observed after anticonvulsant drugs. In two cases PS was observed after ten days and in three after fifteen days of therapy with the offending drug. Three cases of PS were due to carbamazepine and had morbilliform rash and two cases due to phenobarbitone had erythroderma. All had fever, generalised lymphadenopathy and 4/5 had hepatosplenomegaly. Therapy with 15 mg prednisolone daily and withdrawal of the offending drug led to cure in 4/5 cases and one died due to congestive cardiac failure.