Epidermodysplasia Verruciformis with Squamous Cell Carcinoma in a Family
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Sharma VK, Kaur S, Kumar B, Sehgal S. Epidermodysplasia Verruciformis with Squamous Cell Carcinoma in a Family. Indian J Dermatol Venereol Leprol 1985;51:80-86
AbstractThree Indian sibs with epidermodysplasia verruciformis (EV), born of consanguineous marriage, are _described. The lesions were hypopigmented, erythematous, flat papules present over the face, neck, trunk and upper extremities. Multiple Bowen's keratosis over the face in case 1 and 2, and squamous cell carcinomas over the forehead in case 1 and the scalp in case 2 were also present at the time of presentation. Cell-mediated immunity was depressed in all the three case. Viral particles were demonstrated in the nucleus by electronmicroscopy in the lesion of EV. No direct association with any HLA type could be established.