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Evaluation of H2-Receptor antagonists in chronic idiopathic urticaria
Y C Minocha
Department of Dermatology, Venereology and Pharmacology, Dayanand Medical College and Hospital, Ludhiana-141001
|How to cite this article:
Minocha Y C, Minocha K B, Sood V K, Dogra A. Evaluation of H2-Receptor antagonists in chronic idiopathic urticaria. Indian J Dermatol Venereol Leprol 1995;61:265-267
AbstractH1-antagonist (hydroxyzine hydrochloride) in dosage of 10 mg-25 mg thrice a day failed to elicit satisfactory response in 60 out of 170 patients of chronic idiopathic urticaria. Additional administration of H2-antagonist (cimetidine) in dosage of 200 mg four times a day, in patients not responding earlier to H1-antagonist alones exhibited moderate to good improvement of various parameters of urticaria in approximately 85% patients.