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Flagellate pigmentation and sclerodermoid changes: Cutaneous markers of bleomycin toxicity
Ganesh S Pai
Department of Dermatology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Mangalore, Karnataka - 575001
|How to cite this article:
Pai GS, Vimala A M. Flagellate pigmentation and sclerodermoid changes: Cutaneous markers of bleomycin toxicity. Indian J Dermatol Venereol Leprol 1999;65:32-35
Bleomycin therapy causes multiple side effects. Linear or flagellate pigmentation of the skin is a pattern of pigmentation unique to bleomycin therapy. We report 3 cases of testicular tumors on bleomycin therapy, all of whom manifested with flagellate pigmentation on the ncck, trunk and upper limbs and one of whom developed sclerodermoid changes on the arm. Bleomycin, though used in different drug combinations , has consistently resulted in the manifestation of flagellate streaks of pigmentation.