Glucocorticosteroid-induced Osteonecrosis:lessons For the Dermatologist(CME)
|How to cite this article:
Indira D, Snehal S, Sudha C R. Glucocorticosteroid-induced Osteonecrosis:lessons For the Dermatologist(CME). Indian J Dermatol Venereol Leprol 2000;66:173-181
AbstractGlucocorticosteroid therapy can occasionally lead to a serious and debilitating complication called osteonecrosis or avascular necrosis. While a prompt diagnosis of this complication can help in preventing significant morbidity in the affected patients, dermatologists in general, are often not conscious of this facet of steroid-related problems. The precise mechanisms responsible for this disease are not fully understood nor its prevalence in dermatological practice. An attempt has been made in this article to review the current understanding of its pathogenesis, the risk factors associated with its occurrence and the methods for its early diagnosis and treatment. An attempt is also made to formulate a set of guidelines useful to a dermatologist for the prevention of this disabling complication.