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Histochemical Profile of Vitiligo
|How to cite this article:
Koranne R V, Sachdeva K G, Beohar P C. Histochemical Profile of Vitiligo. Indian J Dermatol Venereol Leprol 1988;54:21-23
AbstractFifty untreated vitiligo patients were subjected to histo-chemical examination using dopa reaction technique. Dopa positive melanocytes were absent in a large majority (82%) of cases. Increase in the number of supra-basal clear cells was observed in 70 percent. Presence of inflammatory infiltrate at dermo- epidermal junction along with basal cell layer-dissolution was seen in 7 cases. Grayish-black, void cells considered to be inactive melanocytes, were seen in the basal layer.