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Histological Changes in the Apparently Normal Skin at the Periphery of Leprosy Lesions
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Verma R N, Tutakne M A, Sharma P K. Histological Changes in the Apparently Normal Skin at the Periphery of Leprosy Lesions. Indian J Dermatol Venereol Leprol 1984;50:212
AbstractApparently normal skin at the periphery of the lesions of various types of leprosy has been studied, for histological confinement of the disease. T-r cases showed, good confinement without any histological change in the normal skin, while 21.4% of BT cases, 42.8% of BB cases, 66.6% of BL cases and 80%'of LL cases showed some of the changes viz epidermal atrophy, subepidermal clear zone, acid fast bacilli, attempt at granuloma formation, diffuse lymphocytic infiltration and nerve involvement. Loss of confinement was directly proportional to the expected deficiency in the immune status of the patients from BT to.LL.