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Studies
Influence of liposomal drug entrapment on the performance of corticosteroid creams
GU Rao, RSR Murthy, YS Marfatia, Rajesh Shankar
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Correspondence Address:
G U Rao
Correspondence Address:
G U Rao
| How to cite this article: Rao G U, Murthy R, Marfatia Y S, Shankar R. Influence of liposomal drug entrapment on the performance of corticosteroid creams. Indian J Dermatol Venereol Leprol 1994;60:5-7 |
Copyright: (C)1994 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Skin blanching and clinical efficacy of a liposomally entrapped Triamcinolone acetonide (TRMA) cream was compared with that of the conventional TRMA cream in healthy human volunteers and eczema patients respectively. Both the creams showed equal efficacy in eczema patients. A significant reduction in the skin blanching response with the liposomal TRMA cream as compared to the conventional TRMA cream suggests a decrease in the systemic absorption of the corticosteroid with the former.
Keywords: Liposomes, TRMA, Skin blanching, Clinical profile
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