Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
Filter by Categories
15th National Conference of the IAOMFP, Chennai, 2006
Abstracts from current literature
Acne in India: Guidelines for management - IAA Consensus Document
Art & Psychiatry
Association Activities
Association Notes
Award Article
Book Review
Brief Report
Case Analysis
Case Letter
Case Letters
Case Notes
Case Report
Case Reports
Clinical and Laboratory Investigations
Clinical Article
Clinical Studies
Clinical Study
Conference Oration
Conference Summary
Continuing Medical Education
Cosmetic Dermatology
Current Best Evidence
Current Issue
Current View
Derma Quest
Dermato Surgery
Dermatosurgery Specials
Dispensing Pearl
Do you know?
Drug Dialogues
Editor Speaks
Editorial Remarks
Editorial Report
Editorial Report - 2007
Editorial report for 2004-2005
Fourth All India Conference Programme
From Our Book Shelf
From the Desk of Chief Editor
Get Set for Net
Get set for the net
Guest Article
Guest Editorial
How I Manage?
IADVL Announcement
IADVL Announcements
IJDVL Awards
IJDVL Awards 2018
IJDVL Awards 2019
IJDVL Awards 2020
IJDVL International Awards 2018
Images in Clinical Practice
In Memorium
Inaugural Address
Knowledge From World Contemporaries
Leprosy Section
Letter in Response to Previous Publication
Letter to Editor
Letter to the Editor
Letter to the Editor - Case Letter
Letter to the Editor - Letter in Response to Published Article
Letter to the Editor - Observation Letter
Letter to the Editor - Study Letter
Letter to the Editor - Therapy Letter
Letter to the Editor: Articles in Response to Previously Published Articles
Letters in Response to Previous Publication
Letters to the Editor
Letters to the Editor - Letter in Response to Previously Published Articles
Letters to the Editor: Case Letters
Letters to the Editor: Letters in Response to Previously Published Articles
Medicolegal Window
Miscellaneous Letter
Net Case
Net case report
Net Image
Net Letter
Net Quiz
Net Study
New Preparations
News & Views
Observation Letter
Observation Letters
Original Article
Original Contributions
Pattern of Skin Diseases
Pediatric Dermatology
Pediatric Rounds
Presedential Address
Presidential Address
Presidents Remarks
Report of chief editor
Report of Hon : Treasurer IADVL
Report of Hon. General Secretary IADVL
Research Methdology
Research Methodology
Resident page
Resident's Page
Resident’s Page
Residents' Corner
Residents' Corner
Residents' Page
Review Article
Review Articles
Revision Corner
Self Assessment Programme
Seminar: Chronic Arsenicosis in India
Seminar: HIV Infection
Short Communication
Short Communications
Short Report
Special Article
Specialty Interface
Study Letter
Study Letters
Symposium - Contact Dermatitis
Symposium - Lasers
Symposium - Pediatric Dermatoses
Symposium - Psoriasis
Symposium - Vesicobullous Disorders
Symposium Aesthetic Surgery
Symposium Dermatopathology
Symposium-Hair Disorders
Symposium-Nails Part I
Symposium-Nails-Part II
Systematic Review and Meta-Analysis
Systematic Reviews and Meta-analyses
Systematic Reviews and Meta-analysis
Therapeutic Guideline-IADVL
Therapeutic Guidelines
Therapeutic Guidelines - IADVL
Therapy Letter
Therapy Letters
View Point
What’s new in Dermatology

Translate this page into:

Case Report
PMID: 17664770

Intraoral giant condyloma acuminatum

RR Gupta, U PS Puri, BB Mahajan, SS Sahni, G Garg
 Department of Dermatology, Government Medical College and Hospital, Faridkot-151 203 (Punjab), India

Correspondence Address:
B B Mahajan
Department of Dermatology, Government Medical College and Hospital, Faridkot-151 203 (Punjab)
How to cite this article:
Gupta R R, Puri U P, Mahajan B B, Sahni S S, Garg G. Intraoral giant condyloma acuminatum. Indian J Dermatol Venereol Leprol 2001;67:264-265
Copyright: (C)2001 Indian Journal of Dermatology, Venereology, and Leprology


A case of intraoral giant condyloma acuminatum is reported in a 50- year- old Indian. He did not respond to topical application of podophyllin 20% but responded partially to electric cauterisation. Surgical excision was done to get rid of the warty growh completely. Since there were no skin or genital lesions and no history of marital or extramarital sexual contact the lesion was probably acquired from environmental sources. Nonsexual transmission should be considered especially when the lesions are extragenital.
Keywords: Giant condyloma acuminatum, Oral cavity, Human papilloma virus


The condyloma acuminatum is a benign epithelial proliferation that occurs most frequently on the mucous membranes of perianal and genital areas of men and women.[1] The causative agent of this lesion is papova group viruses.[2] Condylomata acuminata are now thought to be one of the four most common sexually transmitted diseases and second only to genital herpes among the sexually transmissable viruses.[3] Intraoral condyloma acuminatum is rare[4] and has been reported most commonly in the temperate and developed parts of the world. This case is reported because of extreme rarity of the condition and also to focus attention on the nonsexual means of transmission.

Case Report

A 50-year-old man presented in the Dermatology department of Govt. Medical College, Faridkot in March, 1999 with a warty growth of size 5 x 7 cms. covering right half of inner mucosal surface of lower lip which had seedings on the apposing surface of lower gum for the last one year [Figure - 1]. Lesion started as a white pea sized papule in the vestibule portion of oral cavity. It persisted and enlarged slowly for one year to acquire the present size. Both patient and his wife denied history of marital or extra - marital sexual contact for the last 1½ years. About one and a half years back, patient had undergone surgical bone plating under spinal anaesthesia after fracture of both bones of the right lower leg.

On examination, warty growth had pinkish white colour and granular surface with fissures extending into underlying mucous membrane. Surrounding mucous membrane also gave a whitish hue. Genitalia, rectal mucosa and perianal skin were normal with no warty growth. Examination of patient′s wife failed to detect any genital or skin warts.

All the routine investigations were done. All values were within normal limits. VDRL test and ELISA test for HIV 1 and 2 on blood of patient and his wife gave negative results. Biopsy specimen from growth showed parakeratosis, papillomatosis and acanthosis. There was marked koilocytosis of the superficial layer of epithelium. The epithelial papillae were supported by a fibrovascular core with dilated capillaries. Basal layer showed occasional mitosis. These histological features were consistent with those of condyloma acuminatum.

Topically 20% podophyllin in tincture benzoin was applied to the warty growth for three consecutive applications at weekly intervals. Warty growth did not show any sign of regression. Electrocautery of the lesion was done four times at fortnightly interval. Warty growth showed regression up to 75%. As the warty growth had not disappeared completely and was recurrent after electrocauterisation, it was decided to go for surgical excision.


Condyloma acuminatum has been reported to affect the mucous membranes of the gingiva, cheeks, lips and hard palate. This is quite understandable as the oral cavity has a mucocutaneous junction similar to vagina and anus. Some patients with condyloma acuminatum had concurrent genital or anal warts. Some gave a history of oral sex with partners with condylomata acuminata. There were no warts on the genitalia or skin of the patient or his wife. Neither there was any marital or extramarital sexual contact for the last one and a half year nor the patient was in a position to have sexual contact as he was confined to bed for last 1½ years. In this case acquisition of lesions remains an enigma. As there was no history of sexual contact and no other lesions were found on the body, other possible modes of transmission of this virus have to be considered. Transmission of HPV by anogenital contact is clearly possible but non-sexual transmission may also occur.[6] Evidence has suggested that skin and genital warts may be caused by different agents and that skin warts appear to be acquired from environmental sources such as public bathing facilities.[7] Genital warts are acquired sexually with peak occurrence in third decade of life. Further studies are needed of the mode of transmission of papova viruses especially in relation to warts. Meanwhile, nonsexual modes of transmission of this virus may be a real possibility especially when condyloma acuminatum occurs at extragenital sites.

Elder David, Elenitsas Rosalie, Jaworsky Christine, et al. Lever's Histopathology of the Skin. 1997 ; 8th ed ; 583.
[Google Scholar]
Oriel JD, Almeila JD. Demonstration of virus particles in human genital warts. Br J Vener Dis 1970 ; 46 : 37 - 42.
[Google Scholar]
Wright RA, Judson FN. Relative and seasonal incidence of sexually transmitted diseases. A two year statistical review. Br J Vener Dis 1978 ; 54 : 433-440.
[Google Scholar]
Summers L, Booth DR. Intraoral condyloma acuminatum. Oral surg 1974; 38 : 273 - 278.
[Google Scholar]
Marklov VP. Affection of the vermillion border of mucous membrane of the lips in a patient with condyloma acuminatum. Vestn Dermatol Venereol 1971 ; 45 : 69.
[Google Scholar]
Ashiru J0, Ogunbawjo BO, Rotowal NA, et al. Intraoral condylomata acuminata. Br J Vener Dis 1983 ; 59 : 325 - 326.
[Google Scholar]
Oriel JD. Natural history of genital warts. Br J Vener Dis 1971 ; 47: 1-13.1
[Google Scholar]
Show Sections