Linezolid-induced lingua villosa nigra
How to cite this article: Mannu A, Neema S, Vasudevan B. Linezolid-induced lingua villosa nigra. Indian J Dermatol Venereol Leprol doi: 10.25259/IJDVL_560_2022
A 42-year-old lady underwent open reduction and internal fixation for a fracture of the right humerus. She was prescribed oral linezolid 600 mg twice daily and noticed asymptomatic, black discolouration of the tongue on day 4 [Figure 1]. The black hairy tongue or lingua villosa nigra is reported as a rare self-limiting adverse effect of linezolid and is seen in 0.2% of the patients receiving linezolid. The exact mechanism is unclear but could be due to the elongation of the filiform papillae and the overgrowth of chromogenic bacteria and yeast on the dorsal surface of the tongue. Poor oral hygiene is also a risk factor and may have contributed to its development in our case. No specific treatment is required and it resolves spontaneously, as was noted in our case.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent.
Financial support and sponsorship
Conflict of interest
There are no conflicts of interest.