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Mode of inheritance in psoriasis
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Kumar A, Mohan L, Singh K K, Pandey O N, Mu. Mode of inheritance in psoriasis. Indian J Dermatol Venereol Leprol 1992;58:179-182
AbstractOne hundred and eighty patients of psoriasis and 100 controls were analysed to find out the genetic nature of psoriasis and if so, then to determine the possible mode of inheritance. The prevalence of psoriasis in relatives, percentage of positive family history and percentage of total affected relatives in the patient group was significantly higher than the controls, and clustering of affected relatives in patient group suggested genetic involvement. Ratio of affected and unaffected in the sibships with unaffected parents and one parent affected and ratio in the children of patients suggested polygenic mode of inheritance.