Music box spine keratoderma
2 Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
New Colony Soura Srinagar Near Water Supply Control Room, Kashmir
|How to cite this article:
Arif T, Adil M, Rehman S. Music box spine keratoderma. Indian J Dermatol Venereol Leprol 2018;84:182-183
A 60-year-old healthy female presented with gradually increasing, spiky projections on both palms for 5 years. On examination, multiple, discrete, firmly adherent, keratotic papules of the size 1–2 mm were noted over both the palms [Figure - 1]a and [Figure - 1]b. Rest of the cutaneous and systemic examination was unremarkable. Wet contact dermoscopy showed normal skin markings with brownish, keratotic, ovoid projections [Figure - 1]c. Complete hemogram, lipid profile, chest roentgenogram, and abdominal ultrasound were normal. Histopathology of the 3 mm punch skin biopsy showed a sharply defined column of parakeratotic cells with underlying hypogranulosis; other layers of the skin were unremarkable. A diagnosis of spiny keratoderma or “music box spine keratoderma” was made. She was treated with urea and salicylic acid formulation which led to slight improvement. Patient is under follow up to look for development of any systemic diseases or malignancy.
|Figure 1a: Multiple, small 1-2 mm, discrete keratotic papules present over palmar surfaces of both hands|
|Figure 1b: Closer view of the lesions showing brownish colored spiky projections present over palmar surface of hand|
|Figure 1c: Dermoscopy showing brownish, shiny, translucent keratotic papules. Note the normal skin markings and sweat gland openings|
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