Non-surgical (physicochemical) Nail Removal and Antifungal Therapy of Tinea Unguium

Abstract

The ettect of chemo-surgical nail removal with urea ointment followed by 2% miconazole nitrate topical application and/or systemic griseofulvin for three months was studied in 77 mycotic nails. The overall clinical cure was observed in 67.5% nails, consisting of 78.4% fingernails and 46.2% toe-nails. Complete mycological cure was recorded only in 61.0% The cure rates in the finger-nails were 77.8 75.0 and 80.9% in groups I (evulsion + griseofulvin), 11 (evulsion + 2% miconazole) III (evulsion + griseofulvin + 2% and le) respectively, whereas cure -rates nlicOnazO in the toe-nails were 42.8, 44.4 and 50% respectively. Best clinical results (80.9%) were ed in finger-nails treated with a Obtain on of all the three therapeutic Combinati was directly modalities. The cure rate proportional to the extent of nail involvement.