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ORIGINAL CONTRIBUTION
PMID: 28134196
Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis
RB Narayanan, A Girdhar, RK Lavania, BK Girdhar
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| How to cite this article: Narayanan R B, Girdhar A, Lavania R K, Girdhar B K. Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis. Indian J Dermatol Venereol Leprol 1988;54:247-250 |
Copyright: (C)1988 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Langerhans cells (LC) were defined by indirect immunofluoresence using OKT6 monoclonal antibody in the skin lesions of 11 untreated patients with tinea corporis. The number and distribution of OKr6 + epidermal LC in the lesions was very low in comparison to that found in the normal skin. In most of the lesions, T6 + LC could not be seen in the epidermis. A like antigens were not detectable on the keratinocytes. These observations suggest deceased CMI response to the fungal infection and that the reduction in LC may be a contributing factor in the pathogenesis of tinea corporis.Fulltext Views
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