Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis
|How to cite this article:
Narayanan R B, Girdhar A, Lavania R K, Girdhar B K. Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis. Indian J Dermatol Venereol Leprol 1988;54:247-250
AbstractLangerhans cells (LC) were defined by indirect immunofluoresence using OKT6 monoclonal antibody in the skin lesions of 11 untreated patients with tinea corporis. The number and distribution of OKr6 + epidermal LC in the lesions was very low in comparison to that found in the normal skin. In most of the lesions, T6 + LC could not be seen in the epidermis. A like antigens were not detectable on the keratinocytes. These observations suggest deceased CMI response to the fungal infection and that the reduction in LC may be a contributing factor in the pathogenesis of tinea corporis.