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Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi -110029
|How to cite this article:
Sirka C S, Ramam M, Mittal R, Khaitan BK, Verma KK. Olmsted syndrome. Indian J Dermatol Venereol Leprol 1999;65:237-239
A 20-year-old Sikh man had palmoplantar keratoderma, flexion deformity of digits, universal alopecia, keratotic plaques at the angles of mouth, gluteal cleft, knees and dorsal aspects of the metacarpophalangeal joints of the left hand; features of Olmsted syndrome. He had normal nails, teeth, oral mucosa and normal joint movements. Treatment with acitretin, 25mg/day for three and a half months, followed by 25mg once daily alternating with 50 mg once daily for 3 months resulted in significant improvement.