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Oral gugulipid in acne vulgaris management
Jaideep Dogra, Neelam Aneja, VN Saxena
|How to cite this article:
Dogra J, Aneja N, Saxena V N. Oral gugulipid in acne vulgaris management. Indian J Dermatol Venereol Leprol 1990;56:381-383
Copyright: (C)1990 Indian Journal of Dermatology, Venereology, and Leprology
AbstractGugulipid is the standardized extract of the oleo-resin of Commiphora mukul (Burseraceace) an Indian medicinal plant. The active ingredients are two guggulsterones Z and E. Gugulipid is an effective hypolipidemic agent, has a marked antilipolytic activity in rats. Considering the pathogenesis of acne vulgaris and the pharmacological properties of Gugulipid this trial was initiated. Thirty patients with moderate to severe acne ( Grade 4) were included in this study. Tab Guglip was prescribed in tds dosage for 6 weeks. Excellent, good and moderate response was seen in nine (30%) fourteen (46.66%) and seven (23.33%) patients respectively out of the total thirty. No topical treatment was recommended except for local skin -hygiene. The drug showed excellent tolerance. Only three patients (10%) reported relapse when examined at 3 months follow up.
Keywords: Acne Vulgaris, therapy, Gugulipid