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Post kala-azar dermal leishmaniasisa clinico-pathologic study
S M Sinha
|How to cite this article:
Sinha S M, Gupta G, Ghosh R N, Ganguly U, Das A G. Post kala-azar dermal leishmaniasisa clinico-pathologic study. Indian J Dermatol Venereol Leprol 1993;59:172-175
AbstractPost kala-azar dermal leishmaniasis (PKDL), a rare cutaneous lesion is now occurring with increasing frequency in endemic zones in India. Analysis of 20 cases of PKDL revealed previous history of kala-azar in all cases. Types of skin lesions were : hypopigmented macular (75%), erythematous macular (15%) and nodular (10%). Lesions were present mostly in face (64%). Amastigotes of L. donovani were present in 60% of dermal scraping smears and 50% cases on histopathologic examination. Histopathologically 80% showed non-specific mononuclear infiltration, including all the hypopigmented lesions. Amastigotes were detected in 37.5% of these cases. Non-specific compact granuloma was observed in 20% cases including 2 cases each of erythematous and nodular types. Parasites were detected in all these cases.