Response by authors
Vinod K Sharma
Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
|How to cite this article:
Tejasvi T, Sharma VK, Kaur J. Response by authors. Indian J Dermatol Venereol Leprol 2007;73:351
We appreciate the interest and response of Dr. C.R. Srinivas in our publication with regard to the determination of minimal erythema dose (MED) in narrowband UVB (NB-UVB).  The aim of our study was to standardize the MED with an objective parameter using Dermaspectrometer. We did not find statistically significant differences in the visual reading and Dermaspectrometer reading; however, the instrument can detect erythema, which may not be appreciated by eye and avoids subjective variation.
Most of the patients recruited in the study were females ( n=31 out of 41), and we could not find any variation in the MED between the genders. Probably, further studies with no gender bias and more number of subjects could provide a definite answer.
The recruited patients were tested for MED prior to the starting of the NB-UVB treatment, and we started at 70% of their respective MEDs and no patient complained of excessive burning. Hence, the reduction by 50mj from the obtained MED was not practiced by us. In situations where a patient complains of increased sensitivity, the usage of 50% of the MED has been suggested.