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Reversal of systemic sclerosis with dexamethasone pulses
Correspondence Address:
J S Pasricha
How to cite this article: Pasricha J S, Ramam M, Shah S. Reversal of systemic sclerosis with dexamethasone pulses. Indian J Dermatol Venereol Leprol 1990;56:40-42 |
Abstract
A 22 year old female had for the last 8 years,, progressive tightness of the skin along with hyperpigmentation, Raynaud's phenomenon, calcinosis cutis over bony prominences, dysphagia and pulmonary involvement. Treatment with 100 mg dexamethasone given intravenously in 5% dextrose on 3 consecutive days every month led to a significant reversal of all the clinical manifestations over a period of 18 months.