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Letters in Response to Previous Publication
88 (
); 648-649

Salicylic acid peeling in dermatophytosis: An unjustifiable therapy

Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India
Consultant Dermatologist, Katihar, Bihar, India
Department of Dermatology, R. G. Kar Medical College and Hospital, Kolkata, West Bengal, India
Corresponding author: Dr. Anupam Das, Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Das A, Kumar P, Sil A. Salicylic acid peeling in dermatophytosis: An unjustifiable therapy. Indian J Dermatol Venereol Leprol 2022;88:648-9.


We read with interest the article published by Saoji and Madke which discusses the efficacy of salicylic acid in the treatment of dermatophytosis.1 However, we would like to put forward our opinions and concerns on the role of salicylic acid in this notoriously recalcitrant condition:

  1. Dermatophytosis has acquired an epidemic-like magnitude in the present times.2 The prevalence of the disease is reported to be as high as 61.5% in some parts of the country.3 Therefore, to address the management of the situation, if a study is conducted, a properly calculated sample size is quintessential so that the external validity of the results of the study holds significance. Authors have recruited only 35 patients in the study, which we believe is much less than what it should have been.

  2. Authors mention that 36% of study participants developed clinical and microbiological recurrence within a period of four weeks. We believe that this is a big number, considering the very small sample size. Moreover, recurrent dermatophytosis refers to reoccurrence of glabrous tinea after four weeks of stopping treatment following clinical cure.4 In the present study, the duration of follow-up was only four weeks, which proves that salicylic acid peel is not at all adequate for the management of dermatophytosis (since the cases showed reoccurrence) within such a short period.

  3. Salicylic acid 30% is considered to be a superficial chemical peeling agent, which does not penetrate the skin beyond stratum corneum (or granulosum at the most). Spores of dermatophytes are known to reside within the hair follicles, including the vellus hair, which is responsible for non-response to conventional therapy. Infection by non-anthropophilic dermatophytes, previous corticosteroid therapy and excoriation is known to be some of the risk factors behind the involvement of vellus hair.5 The involvement of hair shafts in tinea corporis is fairly common. In fact, Patil et al. reported that the prevalence of ectothrix form of infection is 87.2% (n = 108, Gomori methenamine silver stain).6 Besides, dermatophytes can affect the keratinised portion of the hair (i.e., Adamson’s fringe) and involvement of hair shafts contributes to the chronicity of dermatophyte infection.7 In this scenario, prescribing salicylic acid as a standalone therapy in dermatophytosis lacks scientific rationale. In our opinion, treatment with salicylic acid peel is somewhat analogous to patients’ self-medication of tinea with a well-known proprietary formulation of dithranol (salicylic acid 1.15% w/w + dithranol 1.15% w/w + coal tar 5.3% w/w). Subsequently, patients develop intense irritant contact dermatitis and the epidermis of the affected area is exfoliated in the next 7-to-10 days. One could expect a clearance of dermatophyte infection, but most of the cases go on to recur. Of note, the foci of recurrence are often folliculocentric, highlighting the involvement of hair shafts in chronic cases. In addition, many times, we observe erosions in this kind of irritant contact dermatitis, indicating complete loss of epidermis. If the dithranol formulation cannot achieve clearance, we should not expect clearance with superficial peel, like that with salicylic acid 30%.

  4. Inadvertent use of topical steroid-antifungal preparation has accelerated the on-going tinea pandemic leading to recalcitrant lesions, atypical presentation (tinea pseudoimbricata) and resistance.8 If the practice of salicylic acid peeling for dermatophytoses is adopted by unqualified practitioners, the consequences would be detrimental.

  5. The methodology adopted by the authors to conduct the study is not clear. Out of the cohort of 35 patients in the present study three reported no previous therapeutic intervention. Denying these treatment-naïve patients the standard first-line therapy does not seem to be ethical. Besides, among the patients recruited, clinical resistance was noted to terbinafine in seven, to itraconazole in one, while the rest reported recurrences after initial improvement with antifungal treatment. However, the authors do not specify if any of these patients fulfilled the definition of chronic and recurrent dermatophytosis.4 Given this background, the authors could have rather explored the role of salicylic acid in chronic, resistant and recalcitrant dermatophytoses, where all standard therapeutic options would have been exhausted.

Therefore, although keratolytic agents like salicylic acid have been reported to be useful as an adjuvant therapy in dermatophytoses, recommending them as standalone therapeutic agents is questionable.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.


  1. , . Efficacy of salicylic acid peel in dermatophytosis. Indian J Dermatol Venereol Leprol. 2021;87:671-5.
    [CrossRef] [PubMed] [Google Scholar]
  2. , , , , , , et al. The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-a molecular study. Mycoses. 2019;62:336-56.
    [CrossRef] [PubMed] [Google Scholar]
  3. , , , , , , et al. The unprecedented epidemic-like scenario of dermatophytosis in India: I. Epidemiology risk factors and clinical features. Indian J Dermatol Venereol Leprol. 2021;87:154-75.
    [CrossRef] [PubMed] [Google Scholar]
  4. , , , , , , et al. Indian association of dermatologists, venereologists and leprologists (IADVL) task force against recalcitrant tinea (ITART) consensus on the management of glabrous tinea (INTACT) Indian Dermatol Online J. 2020;11:502-19.
    [Google Scholar]
  5. , . Tinea of vellus hair: An indication for systemic antifungal therapy. Br J Dermatol. 2010;163:603-6.
    [CrossRef] [PubMed] [Google Scholar]
  6. , , , . Histopathology of hair follicle epithelium in patients of recurrent and recalcitrant dermatophytosis: A diagnostic cross-sectional study. Int J Trichology. 2019;11:159-66.
    [CrossRef] [PubMed] [Google Scholar]
  7. , . Pathogenesis of hair infection and black dots in tinea capitis caused by Trichophyton violaceum: A histopathological study. J Cutan Pathol. 1992;19:54-8.
    [CrossRef] [PubMed] [Google Scholar]
  8. , , , . Tinea pseudoimbricata: Observations from a clinicoepidemiological and mycological study from eastern India. 2021 Online ahead of print
    [CrossRef] [Google Scholar]

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