Short contact therapy in psoriasis using derobin oinment

Abstract

Derobin ointment was used for a short contact period of 30 minutes a day for the treatment of 12 patients with chronic plaque psoriasis. Full strength Derobin ointment (containing 1.15% dithranol)was used on the lesions situated on the left side, while the right side lesions were treated with Derobin oitnment diluted with yellow soft:paraffin to a concentration of 0.5% dithranol. At the end of 6 weeks, 75% patients completely cleared using either strength of Derobin. Pigmentation of the peri-lesional skin and irritation were minimal with the diluted formulation.