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Study of Histopathology and Melanogenic Activity in Vitiligo
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Verma K, Sarin R C, Prabhakar B R. Study of Histopathology and Melanogenic Activity in Vitiligo. Indian J Dermatol Venereol Leprol 1980;46:99-103
AbstractIn 30 cases skin biopsy from vitiliginous areas were studied for dopa reaction and in routine sections with H & E. Dopa reaction was completely absent in 24 cases. Epidermal changes were present in 23 cases, and dermal changes in 27 cases. Epidermal changes were hyperkeratosis, thinning of stratum malpighi, spongiosis and dissolution of the basal cell layer. Dermal changes Were round cell in the upper demis as well as hyalinisation, dema and fragmentation of collagen.