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Therapy Letter
89 (
); 122-125

Treatment of spider angioma with copper vapour laser radiation (578 nm) under dermoscopy control

PN Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia
Department of the Health Institute, Clinic of Aesthetic Medicine, Kharkiv, Ukraine
National Medical Research Centre of Children Health, Moscow, Russia
Corresponding author: Dr. Igor V Ponomarev, PN Lebedev Physical Institute of the Russian Academy of Sciences, 53, Leninskiy Prospect, Moscow, 119991, Russian Federation.
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Ponomarev IV, Topchiy SB, Andrusenko YN, Shakina LD. Treatment of spider angioma with copper vapour laser radiation (578 nm) under dermoscopy control. Indian J Dermatol Venereol Leprol 2023;89:122-5.


Spider angioma, also known as spider naevus or spider telangiectasia, is a common benign vascular lesion resulting from dilating arterioles associated with the feeder’s vessel.1 Multiple spider angiomas may be associated with advanced liver disease, thyrotoxicosis or pronounced hormonal changes. The prevalence of spider angioma has been reported up to 15% in adolescents and adults. Patients with spider angioma are mostly looking for treatment due to cosmetic concerns. Sclerotherapy, cryotherapy, fine-needle electrocautery, pulsed dye laser, potassium titanyl phosphate or neodymium-doped yttrium aluminium garnet lasers have been used to treat spider angioma.2 Current treatment modalities of spider angioma can lead to recurrences, hyperpigmentation, hypopigmentation, pain, ulceration and scar formation.3

The pulsed dye laser treatment has shown fair results in the treatment of spider angioma, but 36% of patients have reported purpura and recurrences.3,4 According to data concerning numerical modelling of the photothermal effect of pulsed dye laser on microvessels, its radiation has failed to obturate the feeder vessel reliably in spider telangiectasia due to insufficient fluency and absorption of its irradiation by oxyhemoglobin.4 So far, in high blood velocity vessels, the blood flow does not shut off before erythrocytes expand beyond the vascular lumen via pores in the overheated vessel wall, promoting the occurrence of purpura in vessels with high-flow blood velocity.4 The copper bromide laser at 578 nm has demonstrated high efficacy for the treatment of spider angioma and other telangiectasias in four patients. Table 1 illustrates the comparison of different laser systems for the treatment of spider angioma.

Table 1:: Comparison of different laser systems for treatment of spider angioma
Laser mode Number of treatments Side effects
Pulsed dye laser 585 nm3 1–7 Purpura
Copper bromide laser 578 nm5 3 Mild atrophy
Potassium titanyl phosphate laser 532 nm8 1.4 ± 0.8 3.4%

The copper vapour laser radiation at 578 nm has been used to treat the port-wine stain, telangiectasia and pyogenic granuloma.6,7 Copper vapour laser seems to be very promising to treat spider angioma. In this study, we report successful treatment of spider telangiectasia with dermoscopic confirmation of the complete elimination of dilated vessels using copper vapour laser.

A total of 17 patients (five males and 12 females), with Fitzpatrick skin type I–III, aged 12–30 years old, with medium-size spider angioma (up to 8 mm), were treated from January to October 2020 at the Medical Center LaNezh (Vologda, Russian Federation) and Laser department of the Health Institute (Kharkiv, Ukraine). The clinical characteristics of patients with spider angioma are indicated in Table 2.

Table 2:: Clinical features of patients with spider angiomas
Number of patients 17
Number of spider angiomas 22
Age in years 12–30
Size in mm 2–7
Duration in months 1–18
Dermoscopic pattern Star 20/22
Network 2/22

The lesions were located on the face and trunk [Figures 13]. The dermoscopic evaluation revealed irregular arborizing or branched dilated blood vessels around the core vessel confirming the diagnosis [Figures 2a and 4a].

Figure 1a:: Before treatment: Spider angioma on the left upper part of the chest in a 11 year-old-boy
Figure 1b:: Immediately after copper vapour laser treatment (average power - 0.7 W, exposure time - 0.2 s)
Figure 2a:: Before treatment: Dermoscopy (×10) of spider angioma. The focus is symmetrical, boundaries are clear and the lobular structure is characteristic of eruptive angioma.
Figure 2b:: Immediately after copper vapour laser treatment. Dermoscopy (×10) of spider angioma: the focus has changed and acquired a white-grey tint due to coagulated vessels and cavities.

Informed consent was taken after discussing the risks and benefits of laser treatment. The lesions were treated with copper vapour laser (Yakhroma–Med, Lebedev Physical Institute of Russian Academy of Sciences). The treatment was performed without anaesthesia. The laser settings were as follows: average power of 0.5–0.65 W at yellow (578 nm) wavelength, the exposure time was 0.1–0.2 s and the diameter of the light spot on the skin was 1 mm. The treatment endpoint using a multiple–stacking–pass technique was assumed when the treated area acquired a greyish tint or blanching [Figures 1b, 2b, 3b and 4b].

Figure 3a:: Before treatment: Spider angioma on the right cheek in a 25-year-old woman
Figure 3b:: Two weeks after copper vapour laser treatment: Spider angioma on the right cheek in a 25-year old woman
Figure 4a:: Dermoscopy (×10) of spider angioma before treatment
Figure 4b:: Dermoscopy (×10) of spider angioma after tracing the “legs” surrounding the core vessel. The focus has changed dramatically and acquired a white tint due to obliterated ectatic vessels and cavities.

In Figure 5, we have demonstrated the spider angioma at various steps of laser treatment. Spider angioma is usually treated by tracing the “legs” surrounding the core vessel at an average power of 0.55 W; the exposure time being 0.12 s [Figure 5b]. Following, the power is increased up to 0.65 W, the exposure time increased up to 0.2 s, and the core vessel is sealed [Figure 5c]. The core vessel should be fully obliterated. Treating the radial dilated arterioles legs initially reduces the flow to the central core. The diminished blood flow to the core larger vessel contributes to complete photothermic obliteration of telangiectatic vessels.

Figure 5:: The spider angioma treatment steps: Before treatment (5a), tracing the “legs” surrounding the core vessel (5b), power increases and the core vessel is sealed (5c). Yellow spots indicate the position of the laser pulses during the treatment.

The removal of spider angioma was carried out in a single session. No bleeding or erythema occurred post-treatment. After the procedure, the irradiated skin was treated with a 0.05% chlorhexidine gluconate solution and then epithelializing Bepanthen cream twice a day. Dermoscopy (×10) was used to check if there were some dilated vessels remaining after the laser irradiation. [Figures 2b and 4b].

The irradiated skin healed with crusting and exfoliation for two weeks [Figure 3b]. The treated spider angioma was evaluated 6–8 weeks after treatment. There were no recurrences for 24 months post-laser treatment. The treatment with copper vapour laser provided the complete removal of pyogenic angioma and clearance without adverse effect in any case. Copper vapour laser radiation provided complete removal of spider angioma by the appropriate vascular obliteration due to the high absorption of 578 nm radiation by oxyhaemoglobin in arterioles.

Our study demonstrates an excellent safety profile of copper vapour laser when treating spider angioma without purpura or pigmentary changes with good cosmetic results. Dermoscopy may detect subtle changes in the microvascular structure of the skin during the laser treatment that the naked eye cannot observe and thus improves the results of laser treatment to prevent relapses.

The limitation of the study is the lack of comparative assessment of the optimal copper vapour laser settings for patients with different skin phototypes.


The authors wish to thank Dr. Nataliya Melnikova, Medical Center LaNezh, Vologda, for supporting this study.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms.

Financial support and sponsorship


Conflict of interest

There are no conflicts of interest.


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