Warty squamous cell carcinoma of glans penis

Tasleem Arif¹ , Mohammad Adil¹ , Noora Saeed²

¹ Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
² Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Correspondence Address:
Tasleem Arif
New Colony Soura, Near Water Supply Control Room, Srinagar - 190 011, Jammu and Kashmir
India

A 52-year-old uncircumcised male with no significant past medical history presented with 1-year history of gradually enlarging raised skin lesion over the glans penis. Local examination revealed a large yellow to light brown plaque of size 4–5 cm, woody in consistency, involving the whole glans penis, prepuce, and coronal sulcus [Figure - 1]. Regional lymph nodes were not palpable. Differential diagnosis included warty squamous cell carcinoma, verrucous carcinoma, and giant condyloma acuminatum. Skin biopsy revealed a well-differentiated warty squamous cell carcinoma. Ultrasonography, magnetic resonance imaging(MRI), and computed tomography did not reveal any local nodal or distant metastasis. MRI showed the extension of the tumor in the subepithelial connective tissue space but not involving the blood vessels or adjoining corpora cavernous or corpora spongiosa. The lesion was found to be stage I on Jacksons grading and T1aN0M0 according to AJCC TNM Staging system. A partial penile amputation was done and patient is still under follow-up.

Figure 1: A single yellowish to light brownish warty plaque involving glans, prepuce, and coronal sulcus in a 52-year-old male

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Conflicts of interest

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