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Whorls within walls: Palisaded and encapsulated neuroma
Corresponding author: Dr. Chirag Ashwin Desai, Department of Dermatology, Divya Sparsh Skin & Hair Clinic, Dadar, Mumbai, India. 83.chirag@gmail.com
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Received: ,
Accepted: ,
How to cite this article: Desai CA, Kumar P. Whorls within walls: Palisaded and encapsulated neuroma. Indian J Dermatol Venereol Leprol. doi: 10.25259/IJDVL_1476_2025
A 40-year-old woman presented with an asymptomatic skin coloured lesion on the nose for the past 2 years. On examination, a solitary dome-shaped, firm, and non-tender skin coloured papule on the nose was noted [Figure 1]. Clinical differential diagnoses included fibrous papule of the nose and solitary trichoepithelioma. Biopsy showed a well-circumscribed spindle cell tumour bundled in the form of fascicles, showing nuclear palisading in places. Small clefts and a thin fibrous capsule were seen. A final diagnosis of palisaded and encapsulated neuroma was given [Figures 2a and b]. This case underscores the need to consider this uncommon entity in the differential diagnosis of a solitary facial papule.

- Single skin-coloured dome-shaped papular lesion on the nose.

- Scanner view demonstrating circumscribed spindle cell tumour centred in the dermis (Haematoxylin & eosin, 40x).

- Spindle-shaped cells with wavy nuclei in fascicles with a palisaded appearance (Haematoxylin & eosin, 400x).
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Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.