Study of Serum Copper and Caeruloplasmin in Psoriasis

Abstract

Serum copper and caeruloplasmin levels were estimated in 15 psoriatic patients and 12 normal subjects to evaluate possible relationship between tyrosine's, the cuproenzyme which plays the main role in pigmentation of the skin and the copper in serum and other cuproenzymes. The study demonstrated the raised serum caeruloplas levels, while copper levels arc normal in psoriatic patients. These finding indicate the possibility of lowered levels of directreacting copper, which is the copper in transport needed by tyrosines for pigmentation. The decrease in direct reacting copper as such may be the factor causing depigmentation.