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Xanthoma disseminatum in a young man
Corresponding author: Dr. Dipankar De, Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. dr_dipankar_de@yahoo.in
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Accepted: ,
How to cite this article: Dev A, Thind A, Kaushal P, De D, Vaiphei K. Xanthoma disseminatum in a young man. Indian J Dermatol Venereol Leprol. doi: 10.25259/IJDVL_806_2024
A 37-year-old man presented with asymptomatic, yellowish, reddish-brown papules that were coalescing to form plaques on the face, neck, trunk and, flexures [Figures 1a and 1b]. In addition, he had polydipsia and polyuria, and had recently developed hoarseness of voice and difficulty in breathing.
- Multiple, discrete, yellowish to brownish papules coalescing to form plaques on the face.
- Numerous, discrete yellowish to reddish brown papules coalescing to form plaque on the right axilla.
Histopathological examination of the cutaneous lesions on the neck revealed dense lymphohistiocytic collections in the dermis as well as Touton-type giant cells. Investigations revealed a reduced serum vasopressin level and reduced urine osmolality. An absent posterior pituitary bright spot was observed on magnetic resonance imaging (MRI). Based on these findings, a diagnosis of xanthoma disseminatum with diabetes insipidus was made.1,2
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Conflicts of interest
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of AI-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.
References
- Xanthoma disseminatum in a young patient with diabetes insipidus. Pediatric Dermatol. 2017;34:e144-5.
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