Comparative evaluation of topical corticosteroid creams

Abstract

It is important to have reliable bioassay models for topical steroids and assess their comparative efficacy. In the present study, seven commonly prescribed commercial corticosteroid creams have been evaluated for their efficacy using histamine bioassay method. The results indicated that clobetasol propionate (Excel®) and betamethasone valerate (Betnovate®), fluocinolone acetonide (Supricort®), beclomethasone dipropionate (Beclate®), betamethasone benzoate (Topicasone ®), and dexamethasone trimethyl acetate (Millicortenol ®) in that order of priority.