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Cutaneous metastases from ovarian clear cell carcinoma
Corresponding author: Dr. Jianmin Chang, Department of Dermatology, Beijing Hospital, National Centre of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. changjm0417@126.com
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Received: ,
Accepted: ,
How to cite this article: Liu T, Chang J. Cutaneous metastases from ovarian clear cell carcinoma. Indian J Dermatol Venereol Leprol. doi: 10.25259/IJDVL_1886_2024
A 47-year-old woman presented with a two-month history of skin lesions on the lower abdomen and thighs. Physical examination revealed multiple, erythematous, painful nodules with a hard consistency, poor mobility, partial surface erosions, and marginal red infiltrating patches [Figure 1]. A biopsy of the nodule from the patient’s right thigh showed polygonal and cuboidal cells of varying sizes with clear cytoplasm in the dermis [Figure 2]. Immunohistochemistry results were positive for hepatocyte nuclear factor (HNF)-1β, Napsin A, paired box (PAX)-8, and Wilm’s tumour gene (WT)-1, while negative for estrogen receptor (ER). She was undergoing treatment for stage IIIC ovarian clear cell carcinoma and was diagnosed with cutaneous metastases from the carcinoma.
- Multiple, erythematous nodules on the lower abdomen and thighs with partial surface erosions and marginal red infiltrating patches.
- Histopathology showing polygonal and cuboidal cells of varying sizes in the dermis with clear cytoplasm (Haematoxylin-eosin; 20x).
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Conflicts of interest
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript, and no images were manipulated using AI.
