Relapse in psoriasis after methotrexate
N A Karibasappa
|How to cite this article:
Karibasappa N A, George A. Relapse in psoriasis after methotrexate. Indian J Dermatol Venereol Leprol 1997;63:307-309
Abstract20 patients, 12 males and 8 females with chronic palque psoriasis, not responding to conventional therapy were treated with methotrexate (MTX) in the dose of 15 mg/week, 3 doses, 12th hourly apart, for 4 - 12 weeks. All the cases in which MTX was stopped after attaining remission and giving maintenance therapy of 5 mg/week for 8 weeks had relapsed within 6 weeks to 12 weeks. Premethotrexate or postmethotrexate laboratory investigations were within normal limits. No significant side effects were noted.