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ORIGINAL CONTRIBUTIONS
Serum testosterone, DHEA-S and androstenedione levels in acne
A Hatwal, SK Singh, JK Agarwal, G Singh, HS Bajpai, SS Gupta
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Correspondence Address:
A Hatwal
Correspondence Address:
A Hatwal
| How to cite this article: Hatwal A, Singh S K, Agarwal J K, Singh G, Bajpai H S, Gupta S S. Serum testosterone, DHEA-S and androstenedione levels in acne. Indian J Dermatol Venereol Leprol 1990;56:427-429 |
Copyright: (C)1990 Indian Journal of Dermatology, Venereology, and Leprology
Abstract
Basal serum levels of total testosterone, dehydroepiandosterone sulfate (DHEA, - S) and androstenedione (A4) were measured by radioimmunoassay in 100 patients of acne vulgaris, and in 100 age and sex matched acne free healthy subjects. In males with acne the mean serum testosterone levels were marginally and the DHEAS and A4A levels were significantly higher as compared to controls (p). Females with acne had significantly higher levels of testosterone (p<0.001), DHEA-S (p<0.001) and (p < 0.01) than controls. Our data suggest that increased adrenal androgen levels in plasma may be responsible for treatment resistant acne vulgarism
Keywords: Testosterone. Dehydroepiandrosterone-sulfate. Androstenedione. Acne vulgaris. Adrenal
